By Jair C. Soares, Samuel Gershon
Responding to the explosion of analysis at the pathophysiology and administration of bipolar illness, this thoroughly revised moment variation spans simple mechanisms, neuroimaging, viral etiology, neurofactors, present therapy implications, and smooth theories of the neurobiology of bipolar affliction to face because the so much authoritative reference in this debilitating . Written and edited via the world over lauded specialists within the box, this resource covers an expansive array of issues together with genetic and causal components, neuroendocrinology, neurotransmitters and sign transduction pathways, neuroimaging and neurorecognition, and customers for brand new therapy improvement.
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Additional resources for Bipolar Disorders: Basic Mechanisms and Therapeutic Implications (Medical Psychiatry, 15)
False-positive results due to ethnic stratification (different representation of ethnic groups with different base frequency of the mutated allele in patient and control groups) may be circumvented by using haplotype relative risk analysis for estimation of relative allelic frequency . Probands and their biological parents are genotyped, and alleles not transmitted to the affected offspring are used to construct a simulated control. If a specific allele is associated with the illness, an excess rate of this allele should be present in the affected offspring group as compared with the simulated control group.
2nd ed. Stamford, CT: Appleton & Lange, 1996. Cummings JL. Frontal-subcortical circuits and human behavior. Arch Neurol 50: 873–880, 1993. Logue V, Durward M, Pratt RT, Piercy M, Nixon WL. The quality of survival after rupture of an anterior cerebral aneurysm. Br J Psychiatry 114:137–160, 1968. Boggousslavsky J, Regli F. Anterior cerebral artery territory infarction in the Lausanne Stroke Registry. Arch Neurol 47:144–150, 1990. Amaral DG, Price JL, Pitkanen A, Carmichael ST. Anatomical organization of the primate amygdaloid complex.
12. Heila¨ H, Turpeinen P, Erkinjuntti T. Case study: mania associated with multiple sclerosis. J Am Acad Child Adolesc Psychiatry 34:1591–1595, 1995. 13. Strakowski SM, McElroy SL, Keck PE Jr, West SA. The co-occurrence of mania with medical and other psychiatric disorders. Int J Psychiatry Med 24:305–328, 1994. 14. Sax KW, Strakowski SM. The co-occurrence of bipolar disorder with medical illness. In: Tohen M, ed. Comorbidity in Affective Disorders. New York: Marcel Dekker, 1998, pp 8-1–8-15. 15.
Bipolar Disorders: Basic Mechanisms and Therapeutic Implications (Medical Psychiatry, 15) by Jair C. Soares, Samuel Gershon