Download PDF by John M. Morihisa: Advances in Brain Imaging

By John M. Morihisa

ISBN-10: 1585620289

ISBN-13: 9781585620289

Albany scientific collage, Albany, manhattan. bargains clinicians and researchers superior figuring out of the idea and perform of mind imaging in psychiatry. reports functions to such issues as melancholy, obsessive-compulsive affliction, and schizophrenia. Softcover. DNLM: psychological issues - prognosis.

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Correctly ascertained, functional imaging abnormalities in schizophrenic patients and their relatives may be particularly useful, since they presumably lie closer to gene function than clinical diagnoses that may reflect the interaction of several pathological processes (Cannon et al. 1994). In other complex disorders, Functional Brain Imaging in Psychiatry 15 the endophenotype approach has been used with success. Using subclinical electroencephalogram (EEG) abnormalities as the endophenotype, Greenberg et al.

1993) and Hadnezar et al. (1997) similarly reported extensive cingulate hypometabolism in studies in which subjects performed an auditory CPT (Rosvold et al. 1956) during the uptake phase of the radiotracer. In a study of the relationship between regional brain activity and the symptoms of schizophrenia, resting regional cerebral blood flow in the ACC correlated with patients’ levels of disorganization (Liddle et al. 1992). As with the early resting studies suggesting impaired DLPFC function, these resting studies do not speak to the functional significance of impaired ACC activity in schizophrenia.

O ver the past several years there has been a remarkable surge of interest in the role that deficits in cognition might play in the disability associated with common mental disorders. In the study of schizophrenia, for example, it has become increasingly clear that cognitive deficits—in particular disturbances of attention and memory—are the strongest predictor of functional outcome, far more so than positive and negative symptoms (Green 1996). In parallel with these developments, a whole new field of neuroscience—cognitive neuroscience—has emerged, and rapid advances have been made in our understanding of the neural basis of human cognition.

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Advances in Brain Imaging by John M. Morihisa


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